Cholinesterase · SINGLE PROTEIN · Equus caballus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P81908. Use UniProt P81908 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P81908 as the stable identity anchor, then attach disease evidence before program review.
Cholinesterase
Review this target as Cholinesterase, mapped to UniProt P81908. Sequence length is 574 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cholinesterase as ChEMBL target CHEMBL5763, mapped to UniProt P81908. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cholinesterase |
| Target Type | SINGLE PROTEIN |
| Organism | Equus caballus |
| UniProt | P81908 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cholinesterase |
| UniProt Accession | P81908 |
| Component Type | Protein |
| Sequence Length | 574 aa |
Cholinesterase
Review this target as Cholinesterase, mapped to UniProt P81908. Sequence length is 574 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5201089 | 10.68 | IC50 | 0.021 | Preclinical |
| CHEMBL2158116 | 10.35 | IC50 | 0.04467 | Preclinical |
| CHEMBL5592238 | 10.32 | IC50 | 0.048 | Preclinical |
| CHEMBL5595714 | 10.19 | IC50 | 0.064 | Preclinical |
| CHEMBL5584158 | 10.14 | IC50 | 0.073 | Preclinical |
| CHEMBL5181960 | 10.06 | IC50 | 0.087 | Preclinical |
| CHEMBL5591456 | 10.04 | IC50 | 0.091 | Preclinical |
| CHEMBL5589708 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL5185039 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL5184944 | 9.85 | IC50 | 0.14 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 737 | 4,181 | 5.8 |
| cell-free format | 99 | 549 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-free format | 11 | 15 | 4.7 |
| single protein format | 10 | 68 | 5.2 |