Assay Detail
Binding
CHEMBL4026883
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M1 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillation counting method
6
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-Based Design and Discovery of New M2 Receptor Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 4.70 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4060823 | — | — | 2 | 5.17 |
| CHEMBL667 | ACETYLCHOLINE | 4.0 | 2 | 4.64 |
| CHEMBL4091934 | — | — | 2 | 4.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4060823 | — | Ki | = | 6760.83 | nM | 5.17 |
| CHEMBL4060823 | — | Ki | = | 6800.0 | nM | 5.17 |
| CHEMBL667 | ACETYLCHOLINE | Ki | = | 22908.68 | nM | 4.64 |
| CHEMBL667 | ACETYLCHOLINE | Ki | = | 23000.0 | nM | 4.64 |
| CHEMBL4091934 | — | Ki | = | 52480.75 | nM | 4.28 |
| CHEMBL4091934 | — | Ki | = | 52000.0 | nM | 4.28 |