Assay Detail
ADMET
CHEMBL4124238
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Cytotoxicity against human THP1 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | THP-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.40 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4127396 | — | — | 1 | 4.70 |
| CHEMBL4126156 | — | — | 1 | 4.10 |
| CHEMBL4129600 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4127396 | — | IC50 | = | 19952.62 | nM | 4.70 |
| CHEMBL4126156 | — | IC50 | = | 79432.82 | nM | 4.10 |
| CHEMBL4129600 | — | IC50 | = | 158489.32 | nM | - |