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Assay Detail

CHEMBL4148205

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Trypanopcidal activity against Trypanosoma cruzi Y trypamastigotes infected in African green monkey Vero cells treated for 5 days by Neubauer chamber or MTS dye based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma cruzi
Cell Type Vero
Confidence 1 — Organism
Curated By Intermediate

Target

Trypanosoma cruzi (CHEMBL368)
Type ORGANISM
Organism Trypanosoma cruzi

Publication

Targeting polyamine transport in Trypanosoma cruzi.
Reigada C, Phanstiel O, Miranda MR, Pereira CA.
Eur J Med Chem (2018) 147 : 1 -6
PubMed 29421567 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.28 6.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL558390 1 6.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL558390 IC50 = 520.0 nM 6.28