Assay Detail
Functional
CHEMBL4186904
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Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Podophyllotoxin derivatives as an excellent anticancer aspirant for future chemotherapy: A key current imminent needs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.87 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4214590 | — | — | 1 | 5.92 |
| CHEMBL4205298 | — | — | 1 | 5.92 |
| CHEMBL4216087 | — | — | 1 | 5.92 |
| CHEMBL4217545 | — | — | 1 | 5.92 |
| CHEMBL44657 | ETOPOSIDE | 4.0 | 1 | 5.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4214590 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4205298 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4216087 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4217545 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL44657 | ETOPOSIDE | IC50 | = | 2030.0 | nM | 5.69 |