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Assay Detail

CHEMBL4193829

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to MOR (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Mu-type opioid receptor (CHEMBL233)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Cyclic Biphalin Analogues Incorporating a Xylene Bridge: Synthesis, Characterization, and Biological Profile.
Stefanucci A, Carotenuto A, Macedonio G, Novellino E, Pieretti S, Marzoli F, Szűcs E, Erdei AI, Zádor F, Benyhe S, Mollica A.
ACS Med Chem Lett (2017) 8 : 858 -863
PubMed 28835802 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL200199 BIPHALIN 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL200199 BIPHALIN EC50 = 1.0 nM 9.00