Assay Detail
Functional
CHEMBL4196388
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Antitrypanosomal activity against Trypanosoma brucei Lister 427 bloodstream form after 72 hrs by resazurin dye-based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.85 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4210646 | — | — | 1 | 6.36 |
| CHEMBL4206286 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4210646 | — | EC50 | = | 440.0 | nM | 6.36 |
| CHEMBL4206286 | — | EC50 | = | 4720.0 | nM | 5.33 |