Assay Detail
Functional
CHEMBL4269840
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 72 hrs by MTS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Cyanobufalins: Cardioactive Toxins from Cyanobacterial Blooms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 8.21 | 8.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4282477 | — | — | 1 | 8.28 |
| CHEMBL4293082 | — | — | 1 | 8.14 |
| CHEMBL4282960 | — | — | 1 | - |
| CHEMBL399680 | BUFALIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4282477 | — | EC50 | = | 5.2 | nM | 8.28 |
| CHEMBL4293082 | — | EC50 | = | 7.2 | nM | 8.14 |
| CHEMBL4282960 | — | EC50 | - | — | - | |
| CHEMBL399680 | BUFALIN | EC50 | - | — | - |