Assay Detail
Functional
CHEMBL4307232
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potentiation of PTX-induced anticancer activity in human DU145 cells assessed as reduction in PTX IC50 (Rvb = 13.5 nmol/L)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of analogues of curcumin for treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.26 | 8.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL245412 | ZERUMBONE | — | 1 | 8.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL245412 | ZERUMBONE | IC50 | = | 5.5 | nM | 8.26 |