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Assay Detail

CHEMBL4327083

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Functional
Antiproliferative activity against human NB4 cells after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NB-4
Confidence 1 — Organism
Curated By Autocuration

Target

NB-4 (CHEMBL614188)
Type CELL-LINE
Organism Homo sapiens

Publication

Research advances on anticancer activities of matrine and its derivatives: An updated overview.
Rashid HU, Xu Y, Muhammad Y, Wang L, Jiang J.
Eur J Med Chem (2019) 161 : 205 -238
PubMed 30359819 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.58 5.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL204860 MATRINE 1 5.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL204860 MATRINE IC50 = 2660.0 nM 5.58