Assay Detail
ADMET
CHEMBL4332216
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP3A4 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of novel azaindazole CCR1 antagonist clinical candidates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.77 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4464625 | — | — | 1 | 4.77 |
| CHEMBL4441094 | — | — | 1 | - |
| CHEMBL4456123 | BI 639667 | 1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4464625 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL4441094 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL4456123 | BI 639667 | IC50 | > | 30000.0 | nM | - |