Assay Detail
Functional
CHEMBL4348129
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Cytotoxicity against human A2780 cells incubated for 48 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and anti-cancer evaluation of folic acid-peptide- paclitaxel conjugates for addressing drug resistance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.43 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4442478 | — | — | 1 | 5.85 |
| CHEMBL4469794 | — | — | 1 | 5.71 |
| CHEMBL4555383 | — | — | 1 | 5.57 |
| CHEMBL4459091 | — | — | 1 | 5.55 |
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 5.54 |
| CHEMBL4581642 | — | — | 1 | 4.94 |
| CHEMBL4534246 | — | — | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4442478 | — | IC50 | = | 1420.0 | nM | 5.85 |
| CHEMBL4469794 | — | IC50 | = | 1950.0 | nM | 5.71 |
| CHEMBL4555383 | — | IC50 | = | 2690.0 | nM | 5.57 |
| CHEMBL4459091 | — | IC50 | = | 2790.0 | nM | 5.55 |
| CHEMBL428647 | PACLITAXEL | IC50 | = | 2850.0 | nM | 5.54 |
| CHEMBL4581642 | — | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL4534246 | — | IC50 | = | 13560.0 | nM | 4.87 |