Assay Detail
Functional
CHEMBL4353415
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Cytotoxicity against MDCK cells assessed as decrease in cell viability
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Canis lupus familiaris |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Triptolide: Medicinal chemistry, chemical biology and clinical progress.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.25 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4566346 | — | — | 1 | 6.57 |
| CHEMBL463763 | TRIPTOLIDE | 3.0 | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4566346 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL463763 | TRIPTOLIDE | IC50 | = | 1200.0 | nM | 5.92 |