Assay Detail
Binding
CHEMBL4371113
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Binding affinity to mu opioid receptor (unknown origin) expressed in HEK cells at pH 7.4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.36 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL596 | FENTANYL | 4.0 | 1 | 8.96 |
| CHEMBL4471584 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL596 | FENTANYL | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL4471584 | — | Ki | = | 17.9 | nM | 7.75 |