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Assay Detail

CHEMBL4376483

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Non-competitive inhibition of equine serum BChE using butyrylthiocholine iodide as substrate by Lineweaver-Burk plot analysis
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Equus caballus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cholinesterase (CHEMBL5763)
Type SINGLE PROTEIN
Organism Equus caballus

Publication

Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands.
Bajda M, Łażewska D, Godyń J, Zaręba P, Kuder K, Hagenow S, Łątka K, Stawarska E, Stark H, Kieć-Kononowicz K, Malawska B.
Eur J Med Chem (2020) 185 : 111785 -111785
PubMed 31669851 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.55 6.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4455690 2 6.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4455690 Ki = 281.0 nM 6.55
CHEMBL4455690 Ki = 281.84 nM 6.55