Assay Detail
ADMET
CHEMBL4378090
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Inhibition of CYP3A4 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Development Process for Discovery and Clinical Advancement of Modern Antimalarials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.93 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL303933 | PIPERAQUINE | 3.0 | 1 | 7.05 |
| CHEMBL2058833 | GANAPLACIDE | 2.0 | 1 | 6.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL303933 | PIPERAQUINE | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL2058833 | GANAPLACIDE | Ki | = | 156.0 | nM | 6.81 |