Assay Detail
Functional
CHEMBL4391687
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human A2780 cells assessed as reduction in cell growth measured after 72 hrs by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.14 | 9.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4439731 | — | — | 1 | 9.62 |
| CHEMBL4458738 | — | — | 1 | 9.28 |
| CHEMBL498271 | — | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4439731 | — | IC50 | = | 0.24 | nM | 9.62 |
| CHEMBL4458738 | — | IC50 | = | 0.53 | nM | 9.28 |
| CHEMBL498271 | — | IC50 | = | 3.01 | nM | 8.52 |