Assay Detail
Binding
CHEMBL4402903
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Inhibition of wild-type human P38alpha MAPK expressed in Escherichia coli Rosetta cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Kinase Atlas: Druggability Analysis of Potential Allosteric Sites in Kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.92 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL372764 | PERIFOSINE | 3.0 | 1 | 5.92 |
| CHEMBL4445946 | — | — | 1 | 5.92 |
| CHEMBL4459106 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL372764 | PERIFOSINE | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4445946 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL4459106 | — | IC50 | = | 1200.0 | nM | 5.92 |