Assay Detail
ADMET
CHEMBL4403283
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Inhibition of CYP3A4 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of Novel Resorcinol Amide Derivatives as Potent and Specific Pyruvate Dehydrogenase Kinase (PDHK) Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.52 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4575355 | — | — | 1 | 5.85 |
| CHEMBL4540811 | — | — | 1 | 5.19 |
| CHEMBL4591977 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4575355 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4540811 | — | IC50 | = | 6470.0 | nM | 5.19 |
| CHEMBL4591977 | — | IC50 | < | 1000.0 | nM | - |