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Assay Detail

CHEMBL4403360

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Jurkat
Confidence 1 — Organism
Curated By Autocuration

Target

Jurkat (CHEMBL397)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances in the development of cyclin-dependent kinase 7 inhibitors.
Teng Y, Lu K, Zhang Q, Zhao L, Huang Y, Ingarra AM, Galons H, Li T, Cui S, Yu P, Oumata N.
Eur J Med Chem (2019) 183 : 111641 -111641
PubMed 31514062 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4434871 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4434871 IC50 = 2.0 nM 8.70