Assay Detail
ADMET
CHEMBL4416917
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Inhibition of human CYP2C9 by fluorescence method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Robust 17(R),18(S)-Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogues as Potential Clinical Antiarrhythmic Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.91 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1109 | SULFAPHENAZOLE | 4.0 | 1 | 6.55 |
| CHEMBL4463477 | — | — | 1 | 5.27 |
| CHEMBL4473988 | — | — | 1 | - |
| CHEMBL1802692 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1109 | SULFAPHENAZOLE | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL4463477 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL4473988 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL1802692 | — | IC50 | > | 50000.0 | nM | - |