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Assay Detail

CHEMBL4418247

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human NB4 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NB-4
Confidence 1 — Organism
Curated By Autocuration

Target

NB-4 (CHEMBL614188)
Type CELL-LINE
Organism Homo sapiens

Publication

Use of 2-(substituted phenylamino)benzoic acid fto inhibitor in treating leukemia
(2018)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.24 6.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4567838 1 6.10
CHEMBL4442310 1 5.28
CHEMBL4572939 1 4.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4567838 IC50 = 800.0 nM 6.10
CHEMBL4442310 IC50 = 5300.0 nM 5.28
CHEMBL4572939 IC50 = 44800.0 nM 4.35