Assay Detail
ADMET
CHEMBL4427463
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Cytotoxicity in differentiated human THP1 cells assessed as reduction in cell viability after 3 days by CellTiter-Glo assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | THP-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dehydrozingerone Inspired Styryl Hydrazine Thiazole Hybrids as Promising Class of Antimycobacterial Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.69 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4455126 | — | — | 1 | 4.96 |
| CHEMBL4539172 | — | — | 1 | 4.42 |
| CHEMBL4534306 | — | — | 1 | - |
| CHEMBL4539586 | — | — | 1 | - |
| CHEMBL4551610 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4455126 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL4539172 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL4534306 | — | IC50 | > | 11000.0 | nM | - |
| CHEMBL4539586 | — | IC50 | > | 11000.0 | nM | - |
| CHEMBL4551610 | — | IC50 | > | 11000.0 | nM | - |