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Assay Detail

CHEMBL4427595

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellmans method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Equus caballus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cholinesterase (CHEMBL5763)
Type SINGLE PROTEIN
Organism Equus caballus

Publication

Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands.
Łażewska D, Jończyk J, Bajda M, Szałaj N, Więckowska A, Panek D, Moore C, Kuder K, Malawska B, Kieć-Kononowicz K.
Bioorg Med Chem Lett (2016) 26 : 4140 -4145
PubMed 27445168 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.09 5.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3323035 1 5.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3323035 IC50 = 8200.0 nM 5.09