Assay Detail
Binding
CHEMBL4431477
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of kinase tracer 199 binding to mouse inactive p38alpha (2 to 349 residues) expressed in Escherichia coli by microscale thermophoresis assay
11
Total Activities
11
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 6 | - | - |
| Ki | 5 | 6.85 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL568875 | — | — | 1 | 7.70 |
| CHEMBL4444555 | — | — | 1 | 7.52 |
| CHEMBL85860 | — | — | 1 | 7.00 |
| CHEMBL4453392 | — | — | 1 | 6.14 |
| CHEMBL87277 | — | — | 1 | 5.89 |
| CHEMBL4536623 | — | — | 1 | - |
| CHEMBL4456735 | — | — | 1 | - |
| CHEMBL4438989 | — | — | 1 | - |
| CHEMBL4454979 | — | — | 1 | - |
| CHEMBL4542069 | — | — | 1 | - |
| CHEMBL4466649 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL568875 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL4444555 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL85860 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL4453392 | — | Ki | = | 730.0 | nM | 6.14 |
| CHEMBL87277 | — | Ki | = | 1290.0 | nM | 5.89 |
| CHEMBL4536623 | — | Inhibition | - | % | - | |
| CHEMBL4456735 | — | Inhibition | - | % | - | |
| CHEMBL4438989 | — | Inhibition | - | % | - | |
| CHEMBL4454979 | — | Inhibition | - | % | - | |
| CHEMBL4542069 | — | Inhibition | - | % | - | |
| CHEMBL4466649 | — | Inhibition | - | % | - |