Compound Detail
CHEMBL4444555
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Basic Information
| ChEMBL ID | CHEMBL4444555 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SXYDUPCCSOBLBR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
382.9
MW (Da)
5.78
ALogP
3
HBA
2
HBD
59.0
PSA (Ų)
0.60
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 CHEMBL2336 | Ki | 7.52 | 7.52 | 30.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 | Ki | = | 30.0 | nM | 7.52 | Inhibition of kinase tracer 199 binding to mouse inactive p38alpha (2 to 349 res... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C6MD00262E | Mitogen-activated protein kinase 14 | 3 |
Data from ChEMBL 36 via Core Engine