Assay Detail
Binding
CHEMBL4432496
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Helicobacter pylori ATCC 43504 urease assessed as amount of ammonia after 15 mins by indophenol method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Helicobacter pylori ATCC 43504 |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Urease subunit alpha/Urease subunit beta (CHEMBL3885651) ↗| Type | PROTEIN COMPLEX |
| Organism | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) |
Publication
1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.54 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1219 | RABEPRAZOLE | 4.0 | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1219 | RABEPRAZOLE | IC50 | = | 290.0 | nM | 6.54 |