Assay Detail
Binding
CHEMBL4434403
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Inhibition of CYP11B1 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.89 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3415152 | — | — | 1 | 5.10 |
| CHEMBL3415154 | — | — | 1 | 4.90 |
| CHEMBL3415153 | — | — | 1 | 4.79 |
| CHEMBL3415155 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3415152 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL3415154 | — | IC50 | = | 12620.0 | nM | 4.90 |
| CHEMBL3415153 | — | IC50 | = | 16100.0 | nM | 4.79 |
| CHEMBL3415155 | — | IC50 | = | 16990.0 | nM | 4.77 |