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Assay Detail

CHEMBL4476915

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxic activity against human Jurkat cells assessed as reduction in cell viability incubated for 3 days by ATPlite assay
ChEMBL ↗
55
Total Activities
55
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Jurkat
Confidence 1 — Organism
Curated By Autocuration

Target

Jurkat (CHEMBL397) ↗
Type CELL-LINE
Organism Homo sapiens

Publication

Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors
(2015)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 55 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4575537 — — 1 5.00
CHEMBL4557769 — — 1 5.00
CHEMBL4526749 — — 1 5.00
CHEMBL4571749 — — 1 5.00
CHEMBL4564403 — — 1 5.00
CHEMBL4581487 — — 1 5.00
CHEMBL4560879 — — 1 5.00
CHEMBL4564656 — — 1 5.00
CHEMBL4515132 — — 1 5.00
CHEMBL4568954 — — 1 5.00
CHEMBL4569521 — — 1 5.00
CHEMBL4551916 — — 1 5.00
CHEMBL4572985 — — 1 5.00
CHEMBL4578907 — — 1 5.00
CHEMBL4533706 — — 1 5.00
CHEMBL4539299 — — 1 5.00
CHEMBL4588274 — — 1 5.00
CHEMBL4555382 — — 1 5.00
CHEMBL4573087 — — 1 5.00
CHEMBL4581045 — — 1 5.00
CHEMBL4544865 — — 1 -
CHEMBL4538727 — — 1 -
CHEMBL4517903 — — 1 -
CHEMBL4555437 — — 1 -
CHEMBL4573045 — — 1 -
CHEMBL4566938 — — 1 -
CHEMBL4564482 — — 1 -
CHEMBL4532617 — — 1 -
CHEMBL4559501 — — 1 -
CHEMBL4561829 — — 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4575537 — EC50 = 10000.0 nM 5.00
CHEMBL4573087 — EC50 = 10000.0 nM 5.00
CHEMBL4557769 — EC50 = 10000.0 nM 5.00
CHEMBL4526749 — EC50 = 10000.0 nM 5.00
CHEMBL4571749 — EC50 = 10000.0 nM 5.00
CHEMBL4564403 — EC50 = 10000.0 nM 5.00
CHEMBL4581487 — EC50 = 10000.0 nM 5.00
CHEMBL4560879 — EC50 = 10000.0 nM 5.00
CHEMBL4564656 — EC50 = 10000.0 nM 5.00
CHEMBL4515132 — EC50 = 10000.0 nM 5.00
CHEMBL4568954 — EC50 = 10000.0 nM 5.00
CHEMBL4569521 — EC50 = 10000.0 nM 5.00
CHEMBL4551916 — EC50 = 10000.0 nM 5.00
CHEMBL4572985 — EC50 = 10000.0 nM 5.00
CHEMBL4578907 — EC50 = 10000.0 nM 5.00
CHEMBL4533706 — EC50 = 10000.0 nM 5.00
CHEMBL4539299 — EC50 = 10000.0 nM 5.00
CHEMBL4588274 — EC50 = 10000.0 nM 5.00
CHEMBL4555382 — EC50 = 10000.0 nM 5.00
CHEMBL4581045 — EC50 = 10000.0 nM 5.00
CHEMBL4534386 — EC50 > 100000.0 nM -
CHEMBL4526765 — EC50 > 100000.0 nM -
CHEMBL4581563 — EC50 > 100000.0 nM -
CHEMBL4537983 — EC50 > 100000.0 nM -
CHEMBL4575641 — EC50 > 100000.0 nM -
CHEMBL4513297 — EC50 > 100000.0 nM -
CHEMBL4483581 — EC50 > 100000.0 nM -
CHEMBL4533752 — EC50 > 100000.0 nM -
CHEMBL4483821 — EC50 > 100000.0 nM -
CHEMBL4561556 — EC50 > 100000.0 nM -
CHEMBL1332168 — EC50 > 100000.0 nM -
CHEMBL4592572 — EC50 > 100000.0 nM -
CHEMBL4569325 — EC50 > 100000.0 nM -
CHEMBL4514773 — EC50 > 100000.0 nM -
CHEMBL4533829 — EC50 > 100000.0 nM -
CHEMBL4584727 — EC50 > 100000.0 nM -
CHEMBL4550502 — EC50 > 100000.0 nM -
CHEMBL4580970 — EC50 > 100000.0 nM -
CHEMBL4554374 — EC50 < 10000.0 nM -
CHEMBL4530625 — EC50 > 100000.0 nM -
CHEMBL4544865 — EC50 > 100000.0 nM -
CHEMBL4538727 — EC50 > 100000.0 nM -
CHEMBL4517903 — EC50 > 100000.0 nM -
CHEMBL4555437 — EC50 < 10000.0 nM -
CHEMBL4573045 — EC50 > 100000.0 nM -
CHEMBL4566938 — EC50 > 100000.0 nM -
CHEMBL4564482 — EC50 > 100000.0 nM -
CHEMBL4532617 — EC50 > 100000.0 nM -
CHEMBL4559501 — EC50 > 100000.0 nM -
CHEMBL4561829 — EC50 > 100000.0 nM -