Assay Detail
Functional
CHEMBL4615243
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Zika virus infected in Vero E6 cells assessed as reduction in virus-induced cytopathic effect incubated for 96 hrs by CCK8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Zika virus |
| Cell Type | Vero C1008 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
2-((4-Arylpiperazin-1-yl)methyl)benzonitrile Derivatives as Orally Available Inhibitors of Hepatitis C Virus with a Novel Mechanism of Action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.89 | 5.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4634954 | — | — | 1 | 5.29 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4634954 | — | EC50 | = | 5150.0 | nM | 5.29 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 33000.0 | nM | 4.48 |