Assay Detail
ADMET
CHEMBL4680541
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Antiproliferative activity against human T47D cells assessed as cell growth inhibition at 0.4 to 100 uM after 6 days by XTT assay
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| IC50 | 1 | 4.60 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4435596 | — | — | 1 | 4.60 |
| CHEMBL4777551 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4435596 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL4777551 | — | Activity | - | — | - |