Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4713205

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to HSP90-beta (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Heat shock protein HSP 90-beta (CHEMBL4303)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition.
Mishra SJ,Liu W,Beebe K,Banerjee M,Kent CN,Munthali V,Koren J,Taylor JA,Neckers LM,Holzbeierlein J,Blagg BSJ
J Med Chem (2021) 64 : 1545 -1557
PubMed 33428418 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.75 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4474770 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4474770 Kd = 180.0 nM 6.75