Assay Detail
ADMET
CHEMBL4820828
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Inhibition of CYP3A4 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tricyclic-Carbocyclic RORγt Inverse Agonists-Discovery of BMS-986313.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.83 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4761772 | — | — | 1 | 4.96 |
| CHEMBL4871326 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4761772 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL4871326 | — | IC50 | = | 20000.0 | nM | 4.70 |