Assay Detail
ADMET
CHEMBL4828527
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Inhibition of CYP2D6 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of EEDi-5273 as an Exceptionally Potent and Orally Efficacious EED Inhibitor Capable of Achieving Complete and Persistent Tumor Regression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.76 | 4.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4870920 | — | — | 1 | 4.84 |
| CHEMBL4854800 | — | — | 1 | 4.72 |
| CHEMBL4861394 | — | — | 1 | 4.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4870920 | — | IC50 | = | 14300.0 | nM | 4.84 |
| CHEMBL4854800 | — | IC50 | = | 18900.0 | nM | 4.72 |
| CHEMBL4861394 | — | IC50 | = | 19700.0 | nM | 4.71 |