Assay Detail
Functional
CHEMBL4842466
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Antiviral activity against Varicella zoster virus assessed as inhibition of viral replication
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.70 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL344738 | CF1743 | — | 1 | 9.70 |
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 8.05 |
| CHEMBL3143033 | — | — | 1 | 7.57 |
| CHEMBL31634 | BRIVUDINE | 2.0 | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL344738 | CF1743 | EC50 | = | 0.2 | nM | 9.70 |
| CHEMBL184 | ACYCLOVIR | EC50 | = | 9.0 | nM | 8.05 |
| CHEMBL3143033 | — | EC50 | = | 27.0 | nM | 7.57 |
| CHEMBL31634 | BRIVUDINE | EC50 | = | 3400.0 | nM | 5.47 |