Assay Detail
Binding
CHEMBL4880561
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Homogeneous Time Resolved Fluorescence Assay
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BAY-474
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.96 | 4.96 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Quantification of enzymatic phosphorylation of biotinylated heterocopolymeric polypeptide using HTRF assay technology |
| Target protein type | Target protein type | - | — | Recombinant human MET kinase enzyme domain |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4522773 | BAY-827 | — | 1 | 4.96 |
| CHEMBL4593677 | BAY-474 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4522773 | BAY-827 | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL4593677 | BAY-474 | IC50 | < | 1.0 | nM | - |