Assay Detail

CHEMBL4881480

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Binding

Biochemical ROCK1 assay

ChEMBL ↗

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Target

Rho-associated protein kinase 1 (CHEMBL3231) ↗

Open DB target context

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Primary target Rho-associated protein kinase 1

CHEMBL3231

Anchored from Assay target.

Protein identity Rho-associated protein kinase 1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Rho-associated protein kinase 1 (CHEMBL3231) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe BAY-549

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.22	9.22

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1971943	BAY-549	—	1	9.22

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1971943	BAY-549	IC50	=	0.6	nM	9.22