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Assay Detail

CHEMBL4883064

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Binding
Assay using V79 cell lines (CYP11B1)
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type V79
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cytochrome P450 11B1, mitochondrial (CHEMBL1908)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Data for DCP probe MSD-CYP11B2
SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.85 6.85

Assay Parameters

Parameter Type Value Units Text
Assay publication Assay publication - PMID: 26005536
Target protein type Target protein type - V79 cell lines stably expressing human CYP11B1 enzyme

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3582478 MSD-CYP11B2 1 6.85
CHEMBL3582461 MSD-CYP11B2-Negative-control 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3582478 MSD-CYP11B2 IC50 = 142.0 nM 6.85
CHEMBL3582461 MSD-CYP11B2-Negative-control IC50 > 10000.0 nM -