Assay Detail
Functional
CHEMBL4888146
Review assay metadata, readout intent, target linkage, and publication context from the same page.
CellTiter-Glo luminescent cell viability assay (CTG) with ZR-75-1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | ZR-75-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Data for DCP probe Borussertib
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.84 | 8.30 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 30996949 |
| Target protein type | Target protein type | - | — | ZR-75-1 cells (breast) |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4795065 | Borussertib | — | 1 | 8.30 |
| CHEMBL4802051 | RL2578 | — | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4795065 | Borussertib | EC50 | = | 5.0 | nM | 8.30 |
| CHEMBL4802051 | RL2578 | EC50 | = | 4200.0 | nM | 5.38 |