Assay Detail
Functional
CHEMBL5032720
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human mu opioid receptor expressed in CHO cells assessed as dynamic mass redistribution by DMR assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel Mixed NOP/Opioid Receptor Peptide Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.78 | 8.92 |
| pEC50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285479 | — | — | 1 | 8.92 |
| CHEMBL5081993 | — | — | 1 | 8.64 |
| CHEMBL396460 | NOCICEPTIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285479 | — | EC50 | = | 1.202 | nM | 8.92 |
| CHEMBL5081993 | — | EC50 | = | 2.291 | nM | 8.64 |
| CHEMBL396460 | NOCICEPTIN | pEC50 | - | — | - |