Assay Detail
Functional
CHEMBL5042844
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Antiproliferative activity against human A2780 cells assessed as reduction in cell viability by soft agar assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.40 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5070553 | — | — | 1 | 7.89 |
| CHEMBL4460561 | — | — | 1 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5070553 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL4460561 | — | IC50 | = | 126.0 | nM | 6.90 |