Assay Detail
Functional
CHEMBL5104523
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.95 | 6.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2023279 | — | — | 1 | 6.13 |
| CHEMBL2023280 | — | — | 1 | 6.03 |
| CHEMBL2023277 | — | — | 1 | 5.88 |
| CHEMBL394882 | NOR-BETA-LAPACHONE | — | 1 | 5.87 |
| CHEMBL5200909 | — | — | 1 | 5.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2023279 | — | IC50 | = | 740.0 | nM | 6.13 |
| CHEMBL2023280 | — | IC50 | = | 940.0 | nM | 6.03 |
| CHEMBL2023277 | — | IC50 | = | 1330.0 | nM | 5.88 |
| CHEMBL394882 | NOR-BETA-LAPACHONE | IC50 | = | 1340.0 | nM | 5.87 |
| CHEMBL5200909 | — | IC50 | = | 1380.0 | nM | 5.86 |