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Assay Detail

CHEMBL5105481

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against drug resistant human A2780 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A2780
Confidence 1 — Organism
Curated By Autocuration

Target

A2780 (CHEMBL614004)
Type CELL-LINE
Organism Homo sapiens

Publication

Indoloquinolines as scaffolds for the design of potent G-quadruplex ligands.
Mendes E, Bahls B, Aljnadi IM, Paulo A.
Bioorg Med Chem Lett (2022) 72 : 128862 -128862
PubMed 35716866 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.20 5.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL292124 1 5.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL292124 IC50 = 6300.0 nM 5.20