Assay Detail
Functional
CHEMBL5115059
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Antiproliferative activity against human T47D cells assessed as cell growth inhibition incubated for 4 hrs under normoxia condition by MTT colorimetric assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of 4-((3-oxo-3-phenylpropyl)amino)benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.94 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.50 |
| CHEMBL5203094 | — | — | 1 | 4.37 |
| CHEMBL5204971 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL5203094 | — | IC50 | = | 43100.0 | nM | 4.37 |
| CHEMBL5204971 | — | IC50 | > | 100000.0 | nM | - |