Assay Detail
Binding
CHEMBL5128372
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Bacillus stearothermophilus alpha-glucosidase type IV using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 15 mins followed by substrate addition and measured after 35 mins by microtiter plate reader analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Geobacillus stearothermophilus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent results from non-basic glycosidase inhibitors: How structural diversity can inform general strategies for improving inhibition potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.93 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5188369 | — | — | 1 | 5.31 |
| CHEMBL5178531 | — | — | 1 | 5.19 |
| CHEMBL594088 | SCIRPUSIN A | — | 1 | 5.08 |
| CHEMBL5187352 | — | — | 1 | 4.96 |
| CHEMBL2260735 | — | — | 1 | 4.72 |
| CHEMBL69863 | PICEATANNOL | — | 1 | 4.64 |
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5188369 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL5178531 | — | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL594088 | SCIRPUSIN A | IC50 | = | 8300.0 | nM | 5.08 |
| CHEMBL5187352 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL2260735 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL69863 | PICEATANNOL | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL165 | RESVERATROL | IC50 | = | 24000.0 | nM | 4.62 |