Compound Detail
CHEMBL2260735
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2260735 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PBRNOKNVNSKDQZ-OWOJBTEDSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
260.2
MW (Da)
2.39
ALogP
5
HBA
5
HBD
101.2
PSA (Ų)
0.42
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.72 | 4.615 | 19000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 19000.0 | nM | 4.72 | Inhibition of Bacillus stearothermophilus alpha-glucosidase type IV using p-nitr... | 35367706 |
| Unchecked | IC50 | = | 31050.0 | nM | 4.51 | Inhibition of Saccharomyces cerevisiae alpha-glucosidase using PNPG as substrate... | 31927314 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28576617 | 10.1016/j.bmcl.2017.05.025 | Transient receptor potential cation channel subfamily A member 1 | 2 |
| - | 10.1007/s00044-009-9236-2 | NON-PROTEIN TARGET | 1 |
| - | 10.1007/s00044-009-9236-2 | Radical scavenging activity | 1 |
| 31927314 | 10.1016/j.ejmech.2020.112034 | Unchecked | 1 |
| 31927314 | 10.1016/j.ejmech.2020.112034 | Tissue alpha-L-fucosidase | 1 |
| 31927314 | 10.1016/j.ejmech.2020.112034 | Alpha-mannosidase | 1 |
| 35367706 | 10.1016/j.ejmech.2022.114282 | Unchecked | 1 |
| 35367706 | 10.1016/j.ejmech.2022.114282 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine