Assay Detail
Binding
CHEMBL5137918
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DPCPX from A1AR in rat whole brain assessed as inhibition constant by radioligand competitive binding assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Research progress in pharmacological activities and structure-activity relationships of tetralone scaffolds as pharmacophore and fluorescent skeleton.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.51 | 5.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4535634 | — | — | 1 | 5.79 |
| CHEMBL5178192 | — | — | 1 | 5.79 |
| CHEMBL5198566 | — | — | 1 | 4.94 |
| CHEMBL5170103 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4535634 | — | Ki | = | 1620.0 | nM | 5.79 |
| CHEMBL5178192 | — | Ki | = | 1640.0 | nM | 5.79 |
| CHEMBL5198566 | — | Ki | = | 11400.0 | nM | 4.94 |
| CHEMBL5170103 | — | Ki | > | 100000.0 | nM | - |