Assay Detail
Binding
CHEMBL5140902
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Binding affinity to rat Androgen receptor in African green monkey COS-7 cells measured by whole-cell binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | COS-7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.98 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL166444 | METRIBOLONE | 2.0 | 1 | 8.82 |
| CHEMBL5175338 | — | — | 1 | 7.57 |
| CHEMBL379527 | — | — | 1 | 7.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL166444 | METRIBOLONE | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL5175338 | — | IC50 | = | 27.0 | nM | 7.57 |
| CHEMBL379527 | — | IC50 | = | 29.0 | nM | 7.54 |