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Assay Detail

CHEMBL5140913

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to rat Androgen receptor
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Androgen receptor (CHEMBL3072)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Therapeutic Strategies to Target the Androgen Receptor.
Xiang W, Wang S.
J Med Chem (2022) 65 : 8772 -8797
PubMed 35786895 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.74 7.89
Ki 1 8.21 8.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL197595 1 8.21
CHEMBL1684194 1 7.89
CHEMBL1910411 1 7.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL197595 Ki = 6.2 nM 8.21
CHEMBL1684194 IC50 = 13.0 nM 7.89
CHEMBL1910411 IC50 = 26.0 nM 7.58