Assay Detail

CHEMBL5140934

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Functional

Antiproliferative activity against human T47D cells

ChEMBL ↗

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Target

T47D (CHEMBL614361) ↗

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Primary target T47D

CHEMBL614361

Anchored from Assay target.

Protein identity T47D

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	T47D
Confidence	1 — Organism
Curated By	Autocuration

Target

T47D (CHEMBL614361) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Therapeutic Strategies to Target the Androgen Receptor.

Xiang W, Wang S.
J Med Chem (2022) 65 : 8772 -8797
PubMed 35786895 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.35	7.35

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL491	HYDROXYFLUTAMIDE	2.0	1	7.35

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL491	HYDROXYFLUTAMIDE	IC50	=	45.0	nM	7.35